I decided to go for a totally out-of-the-box-thinking method, and hooked my scanner up to my NAS, with help of VirtualHere. All my problems are gone! My scanner now works like a charm, both the LiDE 220, and the 210.Perhaps not a solution for everyon...
Unfortunately I'll be joining this group... Had the issue first with Lide 210-Windows 8.1, Then Lide 210-Windows 10, and now with Lide 220-Windows 10...