Thanks! This is very usable work-around. A dedicated setting would still be best, but this solves the immediate problem, and is easy to turn on and off.
Same exact problem as Apprentice, even after new install of DPP4 4.20.x on Windows 10 x64 machine.DPP4 wanted to open the Pictures folder. I was able to open an image by right-clicking an image NOT in Pictures, and selecting Open With DPP4.exe. How...