Is the Canon 50mm f/1.8 lens comparable with the Canon 450D?

[yutagg]

I read in a comment that the 450D has no microAF and that this lens was front focusing.

I’m not exactly sure what this means - but does this make this lens unusable/difficult with the 450D?

[ebiggs1]

Pay no attention to what you read, any ef 50mm f1.8 model will work just fine for you. That said 50mm on a Rebel is a tough FL to live with unless you have a specific use for it. It always seems to be either too long to too short for the shot.

[normadel]

Your EOS 450D (also known as Digital Rebel XSi) can use ANY AND EVERY Canon EF and EF-S  mount lens ever made.

What you read are two tiny tidbits of info that you should disregard. 

The 50mm focal length is of questionable value. On your crop-sensor (APS-C) camera body it gives an effective 80 mm lens field of view, which is short telephoto.  While 50 mm is considered a "normal" focal length on a full-frame body, it is not, on your 450D. Whatever focal length the lens is, multiply that by 1.6 to tell you the full-frame equivalent.

A 28 or 35 mm lens would give you a "normal" field of view.