topic PGI/CLI 250 vs 280 in General Discussion https://community.usa.canon.com/t5/General-Discussion/PGI-CLI-250-vs-280/m-p/303013#M21832 <P>I have a printer that takes PGI/CLI 250/251 cartridges and another one that takes&nbsp;PGI/CLI 280/281 cartridges. I know the cartridges are not interchangeable, but I'm curious as to why they aren't? What's the actual difference between the two? Thank you.</P> Sun, 19 Apr 2020 21:30:24 GMT jayandlinds 2020-04-19T21:30:24Z PGI/CLI 250 vs 280 https://community.usa.canon.com/t5/General-Discussion/PGI-CLI-250-vs-280/m-p/303013#M21832 <P>I have a printer that takes PGI/CLI 250/251 cartridges and another one that takes&nbsp;PGI/CLI 280/281 cartridges. I know the cartridges are not interchangeable, but I'm curious as to why they aren't? What's the actual difference between the two? Thank you.</P> Sun, 19 Apr 2020 21:30:24 GMT https://community.usa.canon.com/t5/General-Discussion/PGI-CLI-250-vs-280/m-p/303013#M21832 jayandlinds 2020-04-19T21:30:24Z